Tumor Microenvironment–Responsive Peptide-Based Supramolecular Drug Delivery System
نویسندگان
چکیده
منابع مشابه
Peptide‐based supramolecular hydrogels for delivery of biologics
The demand for therapeutic biologics has rapidly grown over recent decades, creating a dramatic shift in the pharmaceutical industry from small molecule drugs to biological macromolecular therapeutics. As a result of their large size and innate instability, the systemic, topical, and local delivery of biologic drugs remains a highly challenging task. Although there exist many types of delivery ...
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Stefania Galdiero 1,2,* ID and Paula A. C. Gomes 3,* ID 1 Department of Pharmacy, School of Medicine, University of Naples Federico II, Via Mezzocannone 16, 80134 Naples, Italy 2 Interuniversity Research Centre on Bioactive Peptides (CIRPEB), University of Naples Federico II, Via Mezzocannone 16, 80134 Naples, Italy 3 LAQV-REQUIMTE, Department of Chemistry and Biochemistry, Faculty of Sciences,...
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The central problem in cancer chemotherapy is the severe toxic side effects of anticancer drugs on healthy tissues. Invariably the side effects impose dose reduction, treatment delay, or discontinuance of therapy. To limit the adverse side effects of cancer chemotherapy on healthy organs, we proposed a drug delivery system (DDS) with specific targeting ligands for cancer cells. The proposed DDS...
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ژورنال
عنوان ژورنال: Frontiers in Chemistry
سال: 2020
ISSN: 2296-2646
DOI: 10.3389/fchem.2020.00549